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This study was originally planned to follow certain regional papers with a similar account of the family Scrophulariaceae (figwort or foxglove family) for the Middle Atlantic & N. Central States. But it soon seemed preferable to include the southern Appalachians & the whole Atlantic Coastal Plain. The flora of the northern states has been profoundly modified by the glacial epoch, & any understanding of the composition & distribution of our northern flora should also consider the adjoining southern territory where vegetation was little or not affected & from which the north was again populated. So, it was decided to include again the South Atlantic & the West Gulf States. The plan of this study is both more thorough & more comprehensive than earlier efforts. Illus.