Proteostasis and Disease

Proteostasis and Disease
Author: Rosa Barrio
Publisher: Springer Nature
Total Pages: 350
Release: 2020-04-09
Genre: Science
ISBN: 3030382664


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This book, written by members of the European network PROTEOSTASIS, provides an up-to-date review of the research regarding protein homeostasis in health and disease. With new discoveries contributing to the increasing complexity of this topic, the book offers a detailed overview of the pathways regulating protein homeostasis, including autophagy and the ubiquitin protein family. Following a basic introduction, it explains how defects in protein homeostasis contribute to numerous pathologies, including cancer, neurodegeneration, inflammation and a number of rare diseases. In addition, it discusses, the role of protein homeostasis in cellular development and physiology. Highlighting the latest research in the field of protein homeostasis and its implications for various clinically relevant diseases, the book appeals to researchers and clinicians, while also offering a reference guide for scholars who are new to the field.


Proteostasis and Disease
Language: en
Pages: 350
Authors: Rosa Barrio
Categories: Science
Type: BOOK - Published: 2020-04-09 - Publisher: Springer Nature

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This book, written by members of the European network PROTEOSTASIS, provides an up-to-date review of the research regarding protein homeostasis in health and di
Proteostasis and Disease
Language: en
Pages: 348
Authors: Rosa Barrio
Categories: Science
Type: BOOK - Published: 2021-04-24 - Publisher: Springer

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This book, written by members of the European network PROTEOSTASIS, provides an up-to-date review of the research regarding protein homeostasis in health and di
Protein Homeostasis
Language: en
Pages: 0
Authors: Richard I. Morimoto
Categories: Biological transport
Type: BOOK - Published: 2012 - Publisher:

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Proper folding of proteins is crucial for cell function. Chaperones and enzymes that post-translationally modify newly synthesized proteins help ensure that pro
Protein Homeostasis, Second Edition
Language: en
Pages: 562
Authors: Richard I. Morimoto
Categories: Medical
Type: BOOK - Published: 2019 - Publisher: Perspectives Cshl

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The entire life cycle of a protein-from synthesis and folding to transport and degradation-is carefully controlled by the proteostasis network. This network, co
Protein Homeostasis Diseases
Language: en
Pages: 450
Authors: Angel L. Pey
Categories: Science
Type: BOOK - Published: 2020-02-13 - Publisher: Academic Press

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Protein Homeostasis Diseases: Mechanisms and Novel Therapies offers an interdisciplinary examination of the fundamental aspects, biochemistry and molecular biol