Genome Organization And Function In The Cell Nucleus
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Genome Organization And Function In The Cell Nucleus
Author | : Karsten Rippe |
Publisher | : John Wiley & Sons |
Total Pages | : 597 |
Release | : 2011-12-19 |
Genre | : Science |
ISBN | : 3527326987 |
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By way of its clear and logical structure, as well as abundant highresolution illustrations, this is a systematic survey of the players and pathways that control genome function in the mammalian cell nucleus. As such, this handbook and reference ties together recently gained knowledge from a variety of scientific disciplines and approaches, dissecting all major genomic events: transcription, replication, repair, recombination and chromosome segregation. A special emphasis is put on transcriptional control, including genome-wide interactions and non-coding RNAs, chromatin structure, epigenetics and nuclear organization. With its focus on fundamental mechanisms and the associated biomolecules, this will remain essential reading for years to come.
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