Apoptosis in Carcinogenesis and Chemotherapy

Apoptosis in Carcinogenesis and Chemotherapy
Author: George G. Chen
Publisher: Springer Science & Business Media
Total Pages: 396
Release: 2009-02-22
Genre: Medical
ISBN: 140209597X


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Although research on carcinogenesis has focused more on cellular proliferation than on cell death, yet understanding the mechanism of apoptosis may have important implications for cancer therapy. This book brings together experts from around the world who will discuss the common cancers encountered in clinical practice in the laboratory setting. During the induction of these common cancers, the role of apoptosis in cellular and molecular changes is emphasized, critically highlighting possible anti-cancer strategies. For those who are interested in carcinogenesis and for those who are seeking new approaches to anti-cancer therapy, this book is an important reference. It serves not only as a reference of the current understanding of apoptosis in common cancers but also an important bridge between the laboratory and clinical practice. The editors and contributors are to be congratulated in bringing together an important pool of up-to-date knowledge to light and further our interest in this exciting and expanding ?eld. Arthur K. C. Li Emeritus Professor of Surgery The Chinese University of Hong Kong v Preface The role of apoptosis in cancer development and emerging treatment strategies has rapidly expanded over the past few years. The novel discovery in the apoptotic pa- ways and their relevant molecules provides us not only the knowledge how tumors develop but also the opportunity to design new therapeutic tools to prevent or inhibit the growth of tumors with minimal side-effects. Undoubtedly, understanding the events involved at a molecular level can permit the manipulation of apoptosis for therapeutic purposes.


Apoptosis and Cancer
Language: en
Pages: 0
Authors: Seamus J. Martin
Categories: Apoptosis
Type: BOOK - Published: 1997 - Publisher: S. Karger AG (Switzerland)

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The past five years have witnessed an explosion of research efforts in the study of how cells die. This book provides an up-to-date overview of our current know
Apoptosis in Carcinogenesis and Chemotherapy
Language: en
Pages: 396
Authors: George G. Chen
Categories: Medical
Type: BOOK - Published: 2009-02-22 - Publisher: Springer Science & Business Media

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Although research on carcinogenesis has focused more on cellular proliferation than on cell death, yet understanding the mechanism of apoptosis may have importa
Application of Apoptosis to Cancer Treatment
Language: en
Pages: 369
Authors: Mels Sluyser
Categories: Medical
Type: BOOK - Published: 2005-07-14 - Publisher: Springer Science & Business Media

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Novel drugs are being developed which interact with the programmed cell death (apoptotic) machinery in cancer cells, thereby causing these cells to commit suici
Programmed Cell Death in Cancer Progression and Therapy
Language: en
Pages: 0
Authors: Roya Khosravi-Far
Categories: Medical
Type: BOOK - Published: 2010-11-25 - Publisher: Springer

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Programmed cell death (PCD) plays pivotal roles in tumor progression, cancer therapeutics and resistance of tumor cells to therapy. This book examines the mecha
Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases
Language: en
Pages: 0
Authors: Marek Los
Categories: Medical
Type: BOOK - Published: 2014-12-09 - Publisher: Springer

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As our understanding of apoptotic pathway expands, we are coming to realize the great potential of utilizing this pathway to treat diseases such as cancer. The