Antibody Response Following Sars Cov 2 Infection And Implications For Immunity
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Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity
Author | : Haley K. Holmer |
Publisher | : |
Total Pages | : 0 |
Release | : 2022 |
Genre | : |
ISBN | : |
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In January 2022, we published an evolving rapid review, meta-analysis, and data visualization that compared the risk of reinfection in adults with prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to the risk of infection in adults without a prior infection. We found that prior infection with the Alpha variant or the wild-type SARS-CoV-2 virus reduced the risk of another infection by 80-97 percent (pooled estimate 87%; 95% confidence interval [CI] 84-90%) compared with uninfected individuals in studies with a median followup of 8 months (range 4 to 13 months). Protection remained above 80 percent for at least 7 months. Our original review, published in March 2021,2 described the antibody response after infection with the SARS-CoV-2 virus, but found little information on the duration of the response beyond 6 months or on antibody formation in asymptomatic patients or in individuals who are immunocompromised.
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