The P53 Family

The P53 Family
Author: Arnold Jay Levine
Publisher:
Total Pages: 0
Release: 2010
Genre: p53 antioncogene
ISBN: 9780879698300


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This volume offers a comprehensive review of the functions of the p53 family. The contributors examine the normal roles of these transcription factors, their evolution, the regulatory mechanisms that control p53 activity, and the part played by p53 mutations in tumorigenesis.


The P53 Family
Language: en
Pages: 0
Authors: Arnold Jay Levine
Categories: p53 antioncogene
Type: BOOK - Published: 2010 - Publisher:

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This volume offers a comprehensive review of the functions of the p53 family. The contributors examine the normal roles of these transcription factors, their ev
Elucidating the Role of P53 and the P53 Target Gene Siva in Embryonic Development and Tumorigenesis
Language: en
Pages:
Authors: Jeanine Louise Frey Van-Nostrand
Categories:
Type: BOOK - Published: 2014 - Publisher:

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The p53 protein plays a critical role in tumor suppression, as evidenced by its high mutation rate in human tumors and the observation that p53-null mice get ca
Evolutionary History of the P53 Family DNA-binding Domain: Insights from an Alvinella Pompejana Homolog
Language: en
Pages: 0
Authors: Qiang Zhang
Categories:
Type: BOOK - Published: 2022 - Publisher:

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The extremophile Alvinella pompejana, an annelid worm living on the edge of hydrothermal vents in the Pacific Ocean, is an excellent model system for studying f
Polyploidization and Cancer
Language: en
Pages: 157
Authors: Randy Y.C. Poon
Categories: Medical
Type: BOOK - Published: 2011-01-11 - Publisher: Springer Science & Business Media

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Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for sev
P53
Language: en
Pages: 288
Authors: Sue Armstrong
Categories: p53 antioncogene
Type: BOOK - Published: 2014-11-20 - Publisher:

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All of us have lurking in our DNA a most remarkable gene, which has a crucial job - it protects us from cancer. Known simply as p53, this gene constantly scans