The Medicinal Chemist's Guide to Solving ADMET Challenges

The Medicinal Chemist's Guide to Solving ADMET Challenges
Author: Patrick Schnider
Publisher: Royal Society of Chemistry
Total Pages: 541
Release: 2021-08-27
Genre: Science
ISBN: 1788012275


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Medicinal chemistry is a complex science that lies at the very heart of drug discovery. Poor solubility, complex metabolism, tissue retention and slow elimination are just some of the properties of investigational compounds that present a challenge to the design and conduct of ADMET studies. Medicinal chemistry experience and knowledge relating to how a lead structure was modified to solve a specific problem is generally very challenging to retrieve. Presented in a visual and accessible style, this book provides rapid solutions to overcome the universal challenges to optimizing ADMET.


The Medicinal Chemist's Guide to Solving ADMET Challenges
Language: en
Pages: 541
Authors: Patrick Schnider
Categories: Science
Type: BOOK - Published: 2021-08-27 - Publisher: Royal Society of Chemistry

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Medicinal chemistry is a complex science that lies at the very heart of drug discovery. Poor solubility, complex metabolism, tissue retention and slow eliminati
ADMET for Medicinal Chemists
Language: en
Pages: 454
Authors: Katya Tsaioun
Categories: Medical
Type: BOOK - Published: 2011-02-15 - Publisher: John Wiley & Sons

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This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts
The Medicinal Chemist's Guide to Solving ADMET Challenges
Language: en
Pages: 541
Authors: Patrick Schnider
Categories: Science
Type: BOOK - Published: 2021-08-20 - Publisher: Royal Society of Chemistry

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The Medicinal Chemist’s Guide to Solving ADMET Challenges summarizes a series of design strategies and tactics that have been successfully employed across pha
Current Trends in Computational Modeling for Drug Discovery
Language: en
Pages: 311
Authors: Supratik Kar
Categories: Science
Type: BOOK - Published: 2023-06-30 - Publisher: Springer Nature

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This contributed volume offers a comprehensive discussion on how to design and discover pharmaceuticals using computational modeling techniques. The different c
Public Health and Toxicology Issues in Drug Research, Volume 2
Language: en
Pages: 854
Authors: Rakesh Kumar Tekade
Categories: Medical
Type: BOOK - Published: 2024-04-05 - Publisher: Elsevier

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Toxicodynamics in Drug Research, Volume 2: Public Health and Toxicology Issues examines the implications of public health issues and the impact of pharmaceutica