Systems Pharmacology And Pharmacodynamics
Download and Read Systems Pharmacology And Pharmacodynamics full books in PDF, ePUB, and Kindle. Read online free Systems Pharmacology And Pharmacodynamics ebook anywhere anytime directly on your device. We cannot guarantee that every ebooks is available!
Systems Pharmacology and Pharmacodynamics
Author | : Donald E. Mager |
Publisher | : Springer |
Total Pages | : 512 |
Release | : 2016-11-29 |
Genre | : Medical |
ISBN | : 3319445340 |
Download Systems Pharmacology and Pharmacodynamics Book in PDF, Epub and Kindle
While systems biology and pharmacodynamics have evolved in parallel, there are significant interrelationships that can enhance drug discovery and enable optimized therapy for each patient. Systems pharmacology is the relatively new discipline that is the interface between these two methods. This book is the first to cover the expertise from systems biology and pharmacodynamics researchers, describing how systems pharmacology may be developed and refined further to show practical applications in drug development. There is a growing awareness that pharmaceutical companies should reduce the high attrition in the pipeline due to insufficient efficacy or toxicity found in proof-of-concept and/or Phase II studies. Systems Pharmacology and Pharmacodynamics discusses the framework for integrating information obtained from understanding physiological/pathological pathways (normal body function system vs. perturbed system due to disease) and pharmacological targets in order to predict clinical efficacy and adverse events through iterations between mathematical modeling and experimentation.
Systems Pharmacology and Pharmacodynamics Related Books
Pages: 512
Pages: 634
Pages: 479
Pages: 420
Pages: 926