Study Of The Role Of Egl 38 Pax In The Developing Egg Laying System And Germline Cell Survival In Caenorhabditis Elegans
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Study of the Role of EGL-38 PAX in the Developing Egg Laying System and Germline Cell Survival in Caenorhabditis Elegans
Author | : Vandana Rajakumar |
Publisher | : |
Total Pages | : 134 |
Release | : 2007 |
Genre | : |
ISBN | : 9781109834499 |
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egl-38(n578) mutant animals exhibit of high levels of Programmed Cell Death (PCD) in the germline and the soma. Wild-type EGL-38 can transcriptionally regulate the bcl-2 gene, ced-9 in C. elegans. In this dissertation, I performed mosaic analysis for EGL-38 and found that its activity is required in both the germline and soma to promote germline cell survival.
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