Selected Papers Of Frederick Sanger
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Selected Papers of Frederick Sanger
Author | : Frederick Sanger |
Publisher | : World Scientific |
Total Pages | : 680 |
Release | : 1996 |
Genre | : Science |
ISBN | : 9789810224301 |
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This important volume is mainly concerned with the development of methods for ?sequencing? ? that is, determination of the order of the amino acids in proteins and of nucleotides in RNA and DNA. In 1943 the position of only one amino acid in a protein (insulin) was known, and Sanger's first paper resulted in finding a second amino acid. In his final paper in 1982 he describes the determination of a DNA sequence of 48,502 nucleotides. The papers describe the steady improvements in techniques, and exciting biological results revealed by the sequences.
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