PEGylated Protein Drugs: Basic Science and Clinical Applications

PEGylated Protein Drugs: Basic Science and Clinical Applications
Author: Francesco M. Veronese
Publisher: Springer Science & Business Media
Total Pages: 289
Release: 2009-12-30
Genre: Medical
ISBN: 3764386797


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PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.


PEGylated Protein Drugs: Basic Science and Clinical Applications
Language: en
Pages: 289
Authors: Francesco M. Veronese
Categories: Medical
Type: BOOK - Published: 2009-12-30 - Publisher: Springer Science & Business Media

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PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving
Nanoengineering of Biomaterials
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Type: BOOK - Published: 2022-04-18 - Publisher: John Wiley & Sons

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A comprehensive discussion of various types of nanoengineered biomaterials and their applications In Nanoengineering of Biomaterials: Drug Delivery & Biomedical
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Type: BOOK - Published: 2018-02-01 - Publisher: Woodhead Publishing

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Engineering of Biomaterials for Drug Delivery Systems: Beyond Polyethylene Glycol examines the combined issues of PEGylation and viable biomaterials as alternat
In Vivo Glucose Sensing
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Categories: Science
Type: BOOK - Published: 2009-11-19 - Publisher: John Wiley & Sons

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In Vivo Glucose Sensing is a key reference for scientists and engineers working on the development of glucose sensing technologies for the management of diabete
Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment
Language: en
Pages: 433
Authors: Jorge Coelho
Categories: Medical
Type: BOOK - Published: 2013-03-15 - Publisher: Springer Science & Business Media

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This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delive