Drug Discovery And Evaluation Methods In Clinical Pharmacology
Download and Read Drug Discovery And Evaluation Methods In Clinical Pharmacology full books in PDF, ePUB, and Kindle. Read online free Drug Discovery And Evaluation Methods In Clinical Pharmacology ebook anywhere anytime directly on your device. We cannot guarantee that every ebooks is available!
Drug Discovery and Evaluation: Methods in Clinical Pharmacology
Author | : H.Gerhard Vogel |
Publisher | : Springer Science & Business Media |
Total Pages | : 576 |
Release | : 2010-12-15 |
Genre | : Medical |
ISBN | : 3540898905 |
Download Drug Discovery and Evaluation: Methods in Clinical Pharmacology Book in PDF, Epub and Kindle
Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
Drug Discovery and Evaluation: Methods in Clinical Pharmacology Related Books
Pages: 576
Pages:
Pages: 564
Pages: 2118
Pages: 0