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Since the introduction of microscopy, pathologists have noted tumor infiltration by inflammatory cells and presumed that this represents the host's attempt to reject its tumor. Recent advances in the molecular biology of inflammation have revealed the signals involved in attracting inflammatory cells to tumors and, for the most part, these signals are mediated by chemokines and their receptors. Chemokines are low molecular weight proteins that attract and activate specific subsets of leukocytes to the exclusion of others.
Since the introduction of microscopy, pathologists have noted tumor infiltration by inflammatory cells and presumed that this represents the host's attempt to r
Chemokines are hormone-like signaling molecules secreted by cells to signal infection and guide the immune response. Following a decade of basic chemokine resea
This volume, new to The Receptors series, focuses on several areas, including the birth, maturation, and structure of Chemokines; Neutrophil, Dendritic, and Lym
GPCR Signaling in Cancer, Volume 145, the latest release in the Advances in Cancer Research series, highlights recent developments in the area of GPCRs and canc