Autophagy in tumor and tumor microenvironment

Autophagy in tumor and tumor microenvironment
Author: Sujit Kumar Bhutia
Publisher: Springer Nature
Total Pages: 284
Release: 2020-10-24
Genre: Medical
ISBN: 9811569304


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This book deals with the paradoxical role of autophagy in tumor suppression and tumor promotion in cancer cells. Autophagy plays opposing, context-dependent roles in tumors; accordingly, strategies based on inhibiting or stimulating autophagy could offer as potential cancer therapies. The book elucidates the physiological role of autophagy in modulating cancer metastasis, which is the primary cause of cancer-associated mortality. Further, it reviews its role in the differentiation, development, and activation of multiple immune cells, and its potential applications in tumor immunotherapy. In addition, it examines the effect of epigenetic modifications of autophagy-associated genes in regulating tumor growth and therapeutic response and summarizes autophagy’s role in the development of resistance to a variety of anti-cancer drugs in cancer cells. In closing, it assesses autophagy as a potential therapeutic target for cancer treatment. Given its scope, the book offers a valuable asset for all oncologists and researchers who wish to understand the potential role of autophagy in tumor biology.


Autophagy in tumor and tumor microenvironment
Language: en
Pages: 284
Authors: Sujit Kumar Bhutia
Categories: Medical
Type: BOOK - Published: 2020-10-24 - Publisher: Springer Nature

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This book deals with the paradoxical role of autophagy in tumor suppression and tumor promotion in cancer cells. Autophagy plays opposing, context-dependent rol
Autophagy and Cancer
Language: en
Pages: 267
Authors: Hong-Gang Wang
Categories: Medical
Type: BOOK - Published: 2013-03-30 - Publisher: Springer Science & Business Media

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With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regu
Tumor Microenvironment
Language: en
Pages: 160
Authors: Alexander Birbrair
Categories: Medical
Type: BOOK - Published: 2020-02-06 - Publisher: Springer Nature

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This volume discusses recent research advances in cancer biology, focusing on the role of the tumor microenvironment. Taken alongside its companion volumes, Tum
Autophagy in Immune Response: Impact on Cancer Immunotherapy
Language: en
Pages: 242
Authors: Salem Chouaib
Categories: Science
Type: BOOK - Published: 2020-05-25 - Publisher: Academic Press

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Autophagy in Immune Response: Impact on Cancer Immunotherapy focuses on the status and future directions of autophagy with respect to different aspects of its i
Self-Eating on Demand: Autophagy in Cancer and Cancer Therapy
Language: en
Pages: 111
Authors: Patrizia Agostinis
Categories:
Type: BOOK - Published: 2018-02-19 - Publisher: Frontiers Media SA

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Macroautophagy, the major lysosomal pathway for recycling intracellular components including whole organelles, has emerged as a key process modulating tumorigen