Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases

Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases
Author: Marek Los
Publisher: Springer Science & Business Media
Total Pages: 411
Release: 2006-06-20
Genre: Medical
ISBN: 0387236953


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As our understanding of apoptotic pathway expands, we are coming to realize the great potential of utilizing this pathway to treat diseases such as cancer. The book attempts to review, summarize, and speculate on the apoptotic pathways, how are they regulated and how targeted therapies are being used to treat a wide variety of diseases. Special emphasis is placed on cancer since new treatments either being developed or currently in the clinical setting are showing great promise to increase survival rates for cancer patients. Chapters will address the biology behind regulating the apoptotic pathways and what goes wrong in disease states whereas other chapters will concentrate on new therapies targeting apoptotic pathways. The reader by the end of the book should have greater insight into the understanding and utilization of apoptotic pathways to fight diseases such as cancer.


Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases
Language: en
Pages: 411
Authors: Marek Los
Categories: Medical
Type: BOOK - Published: 2006-06-20 - Publisher: Springer Science & Business Media

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As our understanding of apoptotic pathway expands, we are coming to realize the great potential of utilizing this pathway to treat diseases such as cancer. The
Apoptosis and Cancer
Language: en
Pages: 0
Authors: Seamus J. Martin
Categories: Apoptosis
Type: BOOK - Published: 1997 - Publisher: S. Karger AG (Switzerland)

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The past five years have witnessed an explosion of research efforts in the study of how cells die. This book provides an up-to-date overview of our current know
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Categories: Medical
Type: BOOK - Published: 2009-02-22 - Publisher: Springer Science & Business Media

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Although research on carcinogenesis has focused more on cellular proliferation than on cell death, yet understanding the mechanism of apoptosis may have importa
Stress Response Pathways in Cancer
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Pages: 450
Authors: Georg T. Wondrak
Categories: Medical
Type: BOOK - Published: 2014-11-07 - Publisher: Springer

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It is now established that dysregulated cell stress response pathways play a critical role in tumorigenesis, and a refined mechanistic understanding of this phe
Programmed Cell Death in Cancer Progression and Therapy
Language: en
Pages: 362
Authors: Roya Khosravi-Far
Categories: Medical
Type: BOOK - Published: 2007-12-29 - Publisher: Springer Science & Business Media

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Programmed cell death (PCD) plays pivotal roles in tumor progression, cancer therapeutics and resistance of tumor cells to therapy. This book examines the mecha